|    Your patients come to you looking for solutions to correct unwanted signs of aging. Those signs caused by external factors and the natural breakdown in skin function as we age, include: 
 | Fine lines and wrinkles | 
 | Sun and age spots | 
 | Uneven skin tone | 
 | Loss of elasticity and firmness | 
 | Loss of natural skin hydration | You have the ability to Transform their skin with the Obagi Nu-Derm System, proven to improve skin functions so that skin looks and acts younger and healthier.  The Obagi Nu-Derm System uses a unique combination of active and prescription ingredients - including Tretinoin and Hydroquinone 4% - to maximize penetration to all skin layers. The specific dosage and frequency are determined and monitored by you, according to your patient's skin condition, needs and lifestyle. The System triggers our Therapeutic Cascade™ that: 
 | Increases cellular turnover of abundant, healthy keratinocytes, pushing fresh cells to the surface more quickly and promoting old cells to exfoliate faster | 
 | Suppresses melanocyte production reversing and preventing hyperpigmentation | 
 | Promotes the even distribution of melanin, eliminating unwanted dark patches and age spots | 
 | Improves intracellular transcription of keratinocytes, producing healthy, uniform cells for better skin structure | 
 | Stimulates fibroblasts to increase collagen and elastin formation, resulting in stronger, more resilient skin | 
 | Increases GAG synthesis, providing natural hydration and necessary nutrients to the epidermis | 
 | Increases angiogenesis, improving blood flow |  The Obagi Nu-Derm System is best for patients who are willing to commit to a comprehensive skin care protocol and will tolerate side effects. They also can be identified by the following: 
 | Concerned about mild to severe photodamage | 
 | Want to eliminate sun or age spots and have hyperpigmentation | 
 | Have fine lines, wrinkles and laxity | 
 | Experience adult acne | |
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